Join Dr Torben Larsen for a discussion of his comprehensive paper: Comparative effectiveness and safety of non-vitamin K antagonist oral anticoagulants and warfarin in patients with atrial fibrillation: propensity weighted nationwide cohort study.
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You can recap the learnings of this journal club by reading the short, comprehensive highlights report which details the key findings of the discussion.
Despite the wealth of evidence demonstrating their ability to save lives, oral anticoagulants – including both warfarin and NOACs – are often avoided by clinicians, owing to the fear of iatrogenic internal bleeding. However, does this actually happen? This study of patient outcomes in a real-world setting demonstrates that not only do NOACs reduce the risk of stroke, some also feature significantly lower risks of death and major bleeding compared to warfarin.