NOACs in the real world

Join Dr Torben Larsen for a discussion of his comprehensive paper: Comparative effectiveness and safety of non-vitamin K antagonist oral anticoagulants and warfarin in patients with atrial fibrillation: propensity weighted nationwide cohort study.

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Highlights report

You can recap the learnings of this journal club by reading the short, comprehensive highlights report which details the key findings of the discussion.

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Despite the wealth of evidence demonstrating their ability to save lives, oral anticoagulants – including both warfarin and NOACs – are often avoided by clinicians, owing to the fear of iatrogenic internal bleeding. However, does this actually happen? This study of patient outcomes in a real-world setting demonstrates that not only do NOACs reduce the risk of stroke, some also feature significantly lower risks of death and major bleeding compared to warfarin.

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