NOACs in the real world

Join Dr Torben Larsen for a discussion of his comprehensive paper: Comparative effectiveness and safety of non-vitamin K antagonist oral anticoagulants and warfarin in patients with atrial fibrillation: propensity weighted nationwide cohort study.

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Highlights report

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Torben Larsen

Aalborg University Hospital

Aalborg, Denmark


Despite the wealth of evidence demonstrating their ability to save lives, oral anticoagulants – including both warfarin and NOACs – are often avoided by clinicians, owing to the fear of iatrogenic internal bleeding. However, does this actually happen? This study of patient outcomes in a real-world setting demonstrates that not only do NOACs reduce the risk of stroke, some also feature significantly lower risks of death and major bleeding compared to warfarin.

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  • Target audience
    This educational activity is designed for cardiologists, surgeons, primary care physicians, GPs, nurses and any other healthcare professional with an interest or role in atrial fibrillation management.
  • Learning objectives
    After participating in this educational activity, participants will be able to:
    • Describe real-world safety and efficacy data for oral anticoagulants in patients with atrial fibrillation
  • Disclosures
    Prof John Camm:
    • Advisor for: Boehringer Ingelheim, Daiichi Sankyo
    • Consultant (retained) for: Boehringer Ingelheim
    • Received honoraria from: Bayer, Daiichi Sankyo, BMS-Pfizer
    Prof Torben Larsen:
    • On speakers Bureau for: Bayer, BMS-Pfizer, Roche Diagnostics, Boehringer Ingelheim, MSD, AstraZeneca, Takeda Pharma
    • Dr Larsen’s institution has received honoraria from: Janssen Scientific Affairs, LLC, Boehringer Ingelheim

    Staff and reviewer disclosures

    PCM Scientific staff, and others involved with the planning, development, and review of the content for this activity have no relevant affiliations or financial relationships to disclose.
  • Funding
    This independent educational activity is supported by funding from Boehringer Ingelheim. PCM Scientific is the medical education company acting as scientific secretariat and organiser for this programme. The activity is run at arm’s length from the financial supporter and all content is created by the faculty. No funder has had input into the content of the activity.